Organic Chemistry for Life Science

Developing new methodologies for the construction of a broad range of molecules significant in life sciences

Acylalkylation of Arynes Generated from o-Iodoaryl Triflates with Hydrosilanes and Cesium Fluoride

M. Minoshima, K. Uchida, Y. Nakamura, T. Hosoya,

*S. Yoshida

Diverse diaryl sulfide synthesis through consecutive aryne reactions

H. Nakajima, Y. Hazama, Y. Sakata, K. Uchida, T. Hosoya, *S. Yoshida

Chem. Commun., 2021, 57, 2621.

Assembly of four modules onto a tetraazide platform by consecutive 1,2,3-triazole formations

*S. Yoshida, Y. Sakata, Y. Misawa, T. Morita, T. Kuribara, H. Ito, Y. Koike, I. Kii, *T. Hosoya

Chem. Commun., 2021, 57, 899.

Facile Synthesis of Tetraarylpyrazines by Sequential Cross-coupling Approach

Y. Nishiyama, K. Akiyama, Y. Sakata, T. Hosoya, *S. Yoshida

Chem. Lett. 2021, 50, 180.

Selected as Editor’s choice; Open Access

Transition-Metal-Free Synthesis of N-Arylphenothiazines through an N- and S-Arylation Sequence

T. Matsuzawa, T. Hosoya, *S. Yoshida

Sequential conjugation methods based on triazole formation and related reactions using azides

*S. Yoshida

Org. Biomol. Chem. 2020, 18, 1550.

Invited Review; Open Access

Recent review article

Recent original papers

Palladium-Catalyzed Sulfinylation of Aryl- and Alkenylborons with Sulfinate Esters

M. Suzuki, K. Kanemoto, Y. Nakamura, T. Hosoya,

S. Yoshida*