Publication
Original Paper (2020~present / 2016~2019 / before 2015)/Review, book, etc
Faculty of Advanced Engineering
Department of Biological Science and Technology
Acylalkylation of Arynes Generated from o-Iodoaryl Triflates with Hydrosilanes and Cesium Fluoride
◆ 109
M. Minoshima, K. Uchida, Y. Nakamura, T. Hosoya,
*S. Yoshida
Org. Lett. 2021, 23, 1868.
Diverse diaryl sulfide synthesis through consecutive aryne reactions
◆ 107
H. Nakajima, Y. Hazama, Y. Sakata, K. Uchida, T. Hosoya, *S. Yoshida
Chem. Commun. 2021, 57, 2621.

S1PR3–G12-biased agonist ALESIA targets cancer metabolism and promotes glucose starvation
◆ 108
M. Toyomoto, A. Inoue, K. Iida, M. Denawa, I. Kii, F. Marie, N. Kadji, T. Kishi, D. Im, T. Shimamura, H. Onogi, S. Yoshida, S. Iwata, J. Aoki, T. Hosoya, *M. Hagiwara
Cell Chem. Biol. 2021, in press.


Assembly of four modules onto a tetraazide platform by consecutive 1,2,3-triazole formations
◆ 106
*S. Yoshida, Y. Sakata, Y. Misawa, T. Morita, T. Kuribara, H. Ito, Y. Koike, I. Kii, *T. Hosoya
Chem. Commun. 2021, 57, 899.

Transition-Metal-Free Synthesis of N-Arylphenothiazines through an N- and S-Arylation Sequence
◆ 110
T. Matsuzawa, T. Hosoya, *S. Yoshida
Org. Lett. 2021, 23, 2347.

Palladium-Catalyzed Sulfinylation of Aryl- and Alkenylborons with Sulfinate Esters
◆ 111
M. Suzuki, K. Kanemoto, Y. Nakamura, T. Hosoya,
*S. Yoshida
Org. Lett. 2021, 23, 3793..

◆ 112
Nucleophilic transformations of azido-containing carbonyl compounds via protection of azido group
T. Aimi, T. Meguro, A. Kobayashi, *T. Hosoya, *S. Yoshida
Chem. Commun. 2021, 57, 6062.


◆ 113
Facile Synthetic Methods for Diverse N-Arylphenylalanine Derivatives via Transformations of Aryne Intermediates and Cross-Coupling Reactions
T. Kobayashi, T. Hosoya, *S. Yoshida
Bull. Chem. Soc. Jpn. 2021, 94, 1823.

◆ 114
Thioxanthone Synthesis from Benzoic Acid Esters through Directed ortho-Lithiation
A. Kobayashi, T. Matsuzawa, T. Hosoya, *S. Yoshida
Chem. Lett. 2021, 50, 1624. [Selected as Editor's Choice (優秀論文)]
◆ 115
Synthesis of Azidoanilines by the Buchwald–Hartwig Amination
Y. Sakata, S. Yoshida, *T. Hosoya
J. Org. Chem. 2021, 86, 15674.

◆ 116
Multicomponent click assembly through 2-azidoacrylamides
having a nucleophilic amino group
H. Takemura, G. Orimoto, A. Kobayashi, T. Hosoya,
S. Yoshida*
◆ 117
Hydride reduction of o-(fluorosilyl)benzodifluorides for subsequent C–F transformations
R. Idogawa, A. Kobayashi, Y. Kim, K. Shimomori, T. Hosoya, S. Yoshida*
Chem. Commun. 2022, 58, 3521.


◆ 118
Synthesis of Multisubstituted Benzenes from Phenols via Multisubstituted Benzynes
A. Nagai, A. Kobayashi, Y. Sakata, Y. Minami,
K. Uchida, T. Hosoya, S. Yoshida*
Synthesis 2022, 54, 5017.
[Special topic: Aryne Chemistry in Synthesis]

◆ 120
Pyridazine Synthesis from 1,2,4,5-Tetrazines and Alkynes in 1,1,1,3,3,3-Hexafluoro-2-propanol through the Inverse Electron Demand Diels–Alder Reaction
C. Yamamoto, M. Suzuki, S. Yoshida*
Bull. Chem. Soc. Jpn. 2022, 95, 1741. [BCSJ award article]
◆ 119
Azido-type-selective triazole formation by iridium-catalyzed cycloaddition with thioalkynes
K. Sugiyama, Y. Sakata, T. Niwa, S. Yoshida, *T. Hosoya
Chem. Commun. 2022, 58, 6235.


◆ 121
Synthesis of benzo[b]furans from alkynyl sulfoxides and phenols by the interrupted Pummerer reaction
A. Kobayashi, T. Matsuzawa, T. Hosoya, S. Yoshida*
RSC Adv. 2023, 13, 839.

◆ 122
Migrative Thioamination of Aryne Intermediates Generated from o-Iodoaryl Triflates
S. Tabata, M. Minoshima, A. Kobayashi, T. Hosoya, S. Yoshida*

◆ 123
Fluorenones and Xanthones through Intramolecular C–F Arylation.
S. Hamada, S. Yoshida*
Bull. Chem. Soc. Jpn. 2023, in press.

◆ 129
Bromothiolation of Arynes for the Synthesis of 2-Bromobenzenethiol Equivalents
S. Tabata, *S. Yoshida
Org. Lett. 2024, 26, 3816.
◆ 130
Iterative click reactions using trivalent platforms for sequential molecular assembly
G. Orimoto, *S. Yoshida
Chem. Commun. 2024, 60, 5824.
◆ 131
Click assembly through selective azaylide formation
M. Hamada, G. Orimoto, *S. Yoshida
Chem. Commun. 2024, 60, 7930.
◆ 132
Regioselective pyridazine synthesis from tetrazines and alkynyl sulfides
C. Yamamoto, K. Numata, M. Suzuki, *S. Yoshida
Org. Chem. Front. 2024, 11, 6159.
◆ 133
Synthesis of Thiaphenanthridinones from Sulfinate Esters and 2-Borylanilines
K. Nakamura, M. Suzuki, S. Yoshida*
Org. Lett. 2024, 26, 9676.
◆ 135
Thioxanthone Synthesis from Thioureas through Double Aryne Insertion into a Carbon–Sulfur Double Bond
M. Kawada, S. Tabata, Y. Hoshi, S. Yoshida*
Org. Lett. 2025, 27, 827.
◆ 134
Three-step click assembly using trivalent platforms bearing azido, ethynyl, and fluorosulfonyl groups
T. Yasuda, G. Orimoto, *S. Yoshida
Chem. Commun. 2025, 61, 2333.
◆ 136
Synthesis of multisubstituted naphthalenes through consecutive aryne reactions
T. Tanaka, S. Tabata, K. Nakamura, Y. Hazama, Y. Sakata, T. Hosoya, S. Yoshida*
Bull. Chem. Soc. Jpn. 2025, 98, uoaf001. [Selected paper, highlighted in Synfacts]
◆ 137
Synthesis of α-arylacetophenone derivatives by Grignard reactions and transformations of arynes via C–C bond cleavage
Y. Hoshi, S. Tabata, S. Yoshida*
◆ 138
Conditional fluorescent changes of azaylides with fluorescent chromophores
M. Hamada, S. Yoshida*
Chem. Lett. 2025, 54, upaf033.
◆ 127
Facile synthesis of dibenzothiophene S-oxides from sulfinate esters
Y. Kumagai, A. Kobayashi, K. Nakamura, *S. Yoshida
Chem. Commun. 2024, 60, 1611.
◆ 128
Highly substituted benzo[b]furan synthesis through substituent migration
A. Kobayashi, S. Tabata, *S. Yoshida
◆ 126
Multisubstituted naphthalene synthesis from 4-hydroxy-2-pyrones and o-silylaryl triflates
K. Numata, S. Tabata, A. Kobayashi, *S. Yoshida
New J. Chem. 2023, 96, 401
◆ 124
Synthesis of 1,2,3-triazoles using Grignard reactions through the protection of azides
R. Namioka, M. Suzuki, *S. Yoshida
Front. Chem. 2023, 11, 1237878.
◆ 125
Facile synthesis of sulfinate esters from aryl iodides via direct oxidation of thioesters
K. Nakamura, Y. Kumagai, A. Kobayashi, M. Suzuki,
*S. Yoshida
Org. Biomol. Chem. 2023, 21, 6886.



















